kidney failure in dogs
Kidney Failure in Dogs
Types of Kidney Failure in Dogs
There are two types of kidney failure in dogs - acute kidney failure and chronic kidney failure.
Acute kidney failure occurs when there is a sudden decline in kidney function (within hours or days) as a result of toxin exposure (such as antifreeze, raisins, grapes, and some human medications) and bacterial infection.
On the other hand, chronic kidney failure involves a gradual but progressive loss of kidney function. The problem can take weeks, months, or years to develop. Age-related issues are the topmost reasons for kidney failure in dogs. Deterioration of organ structure and function inevitably occur from years of wear and tear.
The size of the dog has been found to influence the age of onset of chronic kidney disease. Early signs of kidney disease in smaller dog breeds may be exhibited when theyre about 10-14 years of age. On the other hand, larger breeds, which are known to have shorter life spans than their smaller counterparts, may develop kidney failure as early as seven years old.
Acute Kidney Failure in Dogs
Signs of Acute Kidney Failure
Dogs with acute kidney failure typically show signs of severe lethargy, vomiting, and reduced appetite. They may be drinking and urinating a lot or not at all.
Causes of Acute Kidney Failure
- One of the most common causes of acute kidney failure in dogs is ingestion of toxins, such as antifreeze, rodenticides, or some human medications (such as ibuprofen). Dogs are such curious creatures and this trait can increase their risks for toxin exposures.
- Infection with a bacterial organism called Leptospirosis can lead to kidney failure in pets and people.
- Various drugs can also cause kidney failure in certain pets.
- Severe infections or illnesses like sepsis or pancreatitis can also lead to acute kidney failure.
- Obstruction of the urinary tract caused by kidney stones or bladder stones that restricts urine flow.
- Anything that decreases the flow of blood through the kidneys, including dehydration, heatstroke, bee stings, or snake bites.
Treatment of Acute Kidney Failure
Acute kidney failure is a serious condition. Aggressive and quick treatment to support the kidneys and manage the underlying cause can be lifesaving. Treatment typically consists of hospitalizing your dog and keeping them on IV fluids, administering anti-nausea medications, administering antibiotics if needed, and ensuring they receive proper nutrition. The treatment may take days to weeks. Rechecking blood work and urine tests will help your vet monitor your dogs response to treatment.
Acute kidney failure can be fatal in over half the cases, even with treatment. Approximately 20% will recover and have chronic kidney disease as a result of the damage and 20% will recover and regain normal kidney function.
Chronic Kidney Failure in Dogs
Older cats are more prone to developing chronic kidney failure compared to dogs, but dogs can also develop this condition. Since this is a slow, progressive process, your dog may not show symptoms immediately. You may notice weight loss or muscle mass loss even though your dog is eating well. You might also notice your dog drinking and urinating more than usual. Its important to note that diabetes can cause similar symptoms.
Diagnosing Chronic Kidney Failure
Early stages of chronic kidney disease can be diagnosed with routine yearly blood work and urine tests before clinical symptoms even develop. If your vet suspects kidney failure, they will recommend basic blood work, urinalysis (urine test), and blood pressure measurements to help diagnose kidney failure, stage the kidney failure, and discuss proper treatments and supportive care.
Kidney failure is staged in 4 levels, with Stage 1 being the mildest and Stage 4 being the most severe.
Treatment for Chronic Kidney Failure
Once your vet has diagnosed and staged your dogs kidney failure, treatment will be discussed. Options can range from medications that lower blood pressure, treatment to reduce protein loss in the urine, intravenous or subcutaneous fluids, potassium replacement, medications to help improve red blood cell levels, and dietary changes.
There are a variety of prescription kidney supportive diets available. These diets can help your dog feel better and live longer, often for years, depending on the stage of kidney failure your dog is experiencing. Since some dogs can be picky eaters, you may need to try a variety of diets to find one they enjoy, so dont be discouraged if they refuse a few types!
Encouraging your dog to drink more water will also help support the kidneys. Canned foods contain more fluids compared to dry kibble, so feeding your dog canned food and eliminating the kibble may be recommended. Adding water or low sodium chicken broth (avoid onions and garlic) to the food can also encourage more water intake. Having multiple water bowls around the house will make it easier for your senior dog to take a drink when they want to.
Home Care for Dogs with Kidney Failure
If your dog has been diagnosed with chronic kidney disease, here are some ways to help your dog have a better and longer life:
- Prescribed medications should be administered exactly as instructed by your veterinarian.
- Keep a close eye on your dogs diet and food intake. If your pet is on a prescription diet, avoid feeding extra treats or snacks.
- Divide your dogs daily ration into several smaller meals given at regular intervals throughout the day.
- Fresh food should always be offered during each mealtime.
- Fresh clean water should be available to the dog at all times.
- If your dog has a poor appetite, try warming the food to just below body temperature. Warming can enhance the taste and flavor of the food and encourage your pet to eat.
- Regular monitoring is very important. Dont skip your pets appointments with your veterinarian for follow-up exams and lab work
Read more:
Urinary Tract Infection (UTI) in Dogs
Canine Hormone-Responsive Urinary Incontinence
My dog has Cushings disease. What does this mean?
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Kidney Failure in Dogs
What Is Kidney Failure in Dogs?
The primary job of the kidneys is to filter the blood by removing waste products and controlling the amount of fluid and nutrients kept in the body and how much is passed in urine.
With any type of kidney failure, this filtering isnt working well, so waste products are not properly removed from the bloodstream and too much fluid is passed in urine along with proteins and electrolytes. As waste products build up in the blood and tissues, dogs can get ulcerations (tears) in the lining of their digestive tract as well.
Kidney failure may also be referred to by terms listed below. The word renal refers to all things related to kidneys, and is often used interchangeably. Failure, insufficiency, and disease are commonly used to describe similar issues with the kidneys.
Kidney disease is often divided into categories based on how long it has been affecting the dog. Acute renal failure occurs in a very short time frame, and is often caused by eating or drinking a toxin or getting a severe infection that harms the kidneys. Chronic kidney disease refers to a process with a more gradual onset or one that has been happening for a longer period of time.
Changes that can occur with an aging pet are often caused by chronic kidney disease, but if a dogs kidneys were damaged by eating a toxic item several months ago and he now has renal failure because of this, it is also known as chronic kidney disease.
Symptoms of Kidney Failure in Dogs
Drinking more water (polydipsia)
More frequent urination (polyuria)
Urinary accidents in house-trained pets
Lack of energy
Refusing to eat
Vomiting
Drooling
Changes in defecation (either diarrhea or constipation)
Weight loss
Mouth sores
Bad breath
Weakness
Causes of Kidney Failure in Dogs
Kidney failure can occur because of an acute event, such as a toxin ingestion or infection that harms the kidneys; degenerative (worsening) changes over time; or an underlying medical condition that damages renal tissues, which can occur due to genetic predispositions in some dog breeds.
Specific causes include:
Ingested toxins
Metabolic diseases
Kidney infections
Autoimmune disease
Cancers
Breeds that are prone to inherited renal failure include:
How Veterinarians Diagnose Kidney Failure in Dogs
Your veterinarian will want to run several tests, in addition to a physical exam, to diagnose kidney failure, such as:
Complete blood count
Chemistry panel
Urinalysis with culture
Abdominal ultrasound
Treatment of Kidney Failure in Dogs
Treatment of kidney failure is based on the severity of the disease and whether it is acute or chronic.
Acute kidney disease is treated with hospitalization and IV fluid therapy to support the kidneys and help them remove wastes. Depending on the cause of the disease, decontamination medications, toxin-binding medications, antibiotics, or medications to support the gastrointestinal tract may be given. In extreme cases, renal dialysis can help the kidneys. This last procedure is rare, only available at some university or veterinary specialty hospitals.
Chronic kidney disease requires careful management of dogs at home. They need to have access to water at all times and be encouraged to drink water. Many dogs have improvements with a prescription kidney diet. Some dogs need to be on medications to control high blood pressure or to protect their stomach. Pets with chronic kidney disease need to see their veterinarian often so that their renal values can be checked. Some dogs with kidney disease need to receive injectable fluids at home or may even need to be hospitalized at times to help their fluid needs.
Recovery and Management of Kidney Failure in Dogs
With acute kidney failure, prognosis is variable depending upon the cause of the disease, how severe the disease is, how damaged the kidneys are, the speed and aggressiveness of treatment, and the dogs response.
For chronic renal failure, long-term prognosis is not good. Most dogs die or are euthanized within a year because of poor quality of life.
The families of dogs with kidney disease should expect to watch them closely and will need to see their veterinarian often, especially as their pets kidney function gets worse. These dogs will be easily dehydrated, as their kidneys are not able to keep water in their bodies. Any infection, vomiting, diarrhea, or changes in appetite or activity could severely dehydrate the pet and worsen the disease.
Kidney Failure in Dogs FAQs
How does kidney failure differ from kidney disease?
Kidney disease is a broader term that includes any problem with the kidneys. Kidney failure is a specific term that means the kidneys cant keep up with filtering waste products and managing fluid levels.
Is kidney failure fatal in dogs?
Depending on the severity and progression of the disease, kidney failure can be fatal.
WRITTEN BY
Laura Russell, DVM, MBA, DABVPVeterinarian
Dr. Russell is a 2003 graduate of the University of Missouri. She is board certified in Canine and Feline Practice, certified in canine...
Kidney Failure in Dogs: Causes, Symptoms & Treatment
In this post, well dive into the causes of kidney failure in dogs, common symptoms you should look out for, available treatment options, and more.
Table of Contents
Pro Tip: Not all pet insurance will cover your vet bills if your dog develops a long-term illness. Thats why its very important to have the right pet insurance plan in place.
Types of kidney failure in dogs
Just like in humans, healthy kidneys in dogs control blood pressure, regulate hydration, remove toxins, release hormones needed to produce red blood cells, and maintain a normal electrolyte balance. If the kidney function is impaired, kidney failure occurs. When the kidneys dont work properly, a number of other organs can be affected, including the brain and heart.
Kidney failure (also called renal failure) in dogs can be chronic or acute:
Chronic kidney failure
This occurs when the kidneys lose function gradually and is typically caused by degeneration related to old age. Chronic kidney failure is the most common type of kidney disease in dogs, occurring in 0.5% to 1% of dogs.
Acute kidney failure
This occurs when a canine's kidney function suddenly decreases, usually within hours or a few days. Its typically caused by a severe kidney infection or the consumption of toxins.
The main difference between these two types of kidney failure is that acute kidney failure can be reversed with timely and aggressive treatment. Chronic kidney failure, on the other hand, cant be reversed or cured and it can only be managed. In most cases, the damage to the kidneys has been happening for more than three months and the kidneys will continue to worsen.
What causes kidney failure in dogs?
Chronic kidney failure in dogs
The exact cause of chronic kidney failure is often difficult to pinpoint because of its slow onset. Early symptoms are usually mild and can be easily overlooked or dismissed.
Dental disease is a leading cause of chronic renal failure in senior dogs. Bacteria build up in the animals teeth and enter the digestive system through eating and drinking, affecting the kidneys ability to filter waste over time.
Chronic kidney failure can also be caused by:
- Congenital diseases or birth defects (such as agenesis, when the dog is born missing one or both kidneys)
- Kidney cancer (renal neoplasia)
- Polycystic kidney disease
- Kidney infections
- Fanconi syndrome
- Elevated calcium (hypercalcemia)
- Kidney stones
- Renal dysplasia
- Immune system dysfunction
- Poor blood flow to the kidneys
- Blocked urine movement or flow
- Certain medications (such as NSAIDs and some antibiotics)
Acute renal failure can also lead to chronic renal failure.
Acute kidney failure in dogs
Acute renal failure is most often a result of a dog ingesting poison. It might be antifreeze, household cleaners, or certain drugs. Some human foods like grapes and raisins have also been known to cause kidney failure if eaten frequently and in larger quantities.
Severe bacterial infections can also cause acute kidney failure. Even though kidney infections can occur spontaneously, theres usually a reason why the dog has trouble fighting off the infection, such as urine blockage or kidney stones.
Leptospirosis is one example of a bacterial infection that can cause sudden renal failure in pups. Our canine companions can get leptospirosis by coming into contact with infected urine, water, soil, water, food or bedding, or through a bite from an infected animal. Be sure to talk to your vet about vaccinating against this disease.
Kidney issues can also result from decreased blood flow through the kidneys. This can be caused by severe dehydration (usually from severe diarrhea or vomiting), heatstroke, or snake bites, and bee stings.
Signs of kidney failure in dogs
The most common symptoms in dogs with kidney failure include:
- Excessive thirst and urination
- Lethargy
- Decreased appetite
- Weight loss
- Bad breath
- Pale gums
- Vomiting
- Blood in urine
- Ulcers in the mouth
- Uncoordinated movement such as stumbling
- Intestinal seizures
Dogs with chronic renal failure might not show any clinical signs at first, or the signs might be very subtle.
In severe renal failure, the amount of urine might actually decrease, or the dog might stop making urine altogether. As the condition worsens, other symptoms may include blood in the stool, black or tarry stool, or vomiting blood.
Diagnosing kidney failure in dogs
Blood and urine tests are commonly performed to diagnose kidney failure. Other tests, such as ultrasound, X-rays, and special blood tests might be needed in order to assess the severity of the disease and determine the cause for the failure. In some cases, a biopsy of the kidney might be recommended.
How to treat kidney failure in dogs
Treatment for kidney failure in dogs will depend on the severity of the condition and the underlying reason that caused their kidney to fail.
Dogs with acute renal failure can get very ill and might need to be hospitalized. Milder cases can be treated with antibiotics and fluids on an outpatient basis.
In some cases, dialysis might be necessary. Signs that indicate dialysis should be considered include very high potassium levels, lack of improvement in lab results while the pet receives intravenous fluids, and fluid in the lungs. Both hemodialysis and peritoneal dialysis can be effective but are generally quite expensive.
While damage from acute renal failure is more easily treated, chronic renal failure will cause irreversible damage to your dogs kidneys unless caught early. For that reason, veterinarians generally focus on slowing down the progression of the disease and finding ways to improve the dogs quality of life, usually with medication and diet changes.
Your pups treatment plan might also include:
- Electrolytes to balance out blood levels
- Medications that encourage the production of urine
- Medications to ease gastrointestinal problems
- Medications to reduce vomiting
- Medications for anemia
- Blood pressure management
If kidney disease is left untreated, end-stage renal failure might occur, leading to death. If you suspect your pet has kidney failure, contact your veterinarian or take your dog to an emergency clinic for a diagnosis and treatment.
Cost to treat dogs kidney failure
The cost of diagnosis and treatment will also depend on the cause, as well as on how the dog responds. Initial diagnostic tests usually range between $200 and $750, whereas long-term management of chronic kidney failure can cost between $100 and $500 per month, depending on the prescribed medications and how often IV fluid therapy is required.
Pro Tip: Every dog owner should consider pet insurance. Even if you believe you have enough money to cover veterinary costs, pet insurance could still save you thousands of dollars if your dog gets sick or injured.
Whats the prognosis?
Kidney failure is a very serious disease and about 60% of pets suffering from it will either die or be euthanized because of it. In cases when medical treatment has failed, the chance of survival without dialysis is extremely low. About half of the patients that receive dialysis will recover, depending on what caused the failure. Many of them will recover only partially and end up with permanent kidney damage.
However, some pups manage to recover completely and have a good quality of life for years after being diagnosed with the disease.
Talk to your vet about what you should expect after your dog has been diagnosed and treated for kidney failure. The vet might recommend nutritional supplements and/or a therapeutic diet to manage your pups condition.
Preventing kidney failure in dogs
Considering the fact that acute renal failure is usually caused by ingesting toxins or foods like raisins, preventing it is fairly easy. Make sure to get any poisons, medications, and dog-unsafe foods out of your pups reach. You can also get your dog vaccinated for Leptospirosis.
Chronic renal failure is usually age-related and genetically predetermined, so theres not much you can do to prevent it. However, taking your pet for annual wellness checkups and physical exams can increase the chances of catching the disease early and start treatment before it progresses and becomes more serious.
